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Biomni is an open-source framework designed for autonomous biomedical research, enabling Claude to perform advanced tasks across genomics, drug discovery, and clinical analysis. It leverages a massive 11GB integrated data lake of biological knowledge—including Ensembl, UniProt, and PubMed—to conduct everything from CRISPR screen designs and single-cell RNA-seq analysis to ADMET predictions for drug candidates. This skill is essential for researchers and bioinformaticians who need to automate complex reasoning pipelines, generate executable analysis code, and interpret multi-domain biological data with high precision within their development environment.