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The Biopython skill empowers Claude to act as a specialized bioinformatics assistant, leveraging the industry-standard Biopython toolkit. It provides specific implementation patterns for sequence manipulation, file I/O for formats like FASTA and GenBank, and structural biology analysis. This skill is particularly useful for researchers needing to automate NCBI database queries via Entrez, manage BLAST workflows, analyze protein structures from PDB files, or construct phylogenetic trees, ensuring best practices in computational molecular biology are followed.