Are there any usage limits for the ClinPGx API?

Yes, the API is limited to 2 requests per second. For substantial or high-volume API use, it is recommended to contact the ClinPGx team directly.

Does this skill require an API key for authentication?

No, authentication is not required for basic access to the ClinPGx REST API, making it easy to integrate for standard queries.

What types of genes are covered in the database?

The database covers key pharmacogenes including CYP450 enzymes (CYP2D6, CYP2C19), transporters (SLCO1B1), metabolizers (TPMT, DPYD), and HLA genes.

What is the ClinPGx Database skill used for?

This skill allows AI agents to access curated pharmacogenomics data, helping developers and clinicians find information on how genetics affect drug metabolism, efficacy, and toxicity.

Can I get CPIC dosing recommendations through this skill?

Yes, the skill can query evidence-based clinical practice guidelines from CPIC, including dosing recommendations based on specific genotypes and phenotypes.

ClinPGx Database

Name: ClinPGx Database
Author: x-cmd

byx-cmd

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Ciencia de Datos y ML

Provides programmatic access to comprehensive pharmacogenomics data for precision medicine, clinical guidelines, and gene-drug interaction analysis.

Acerca de

ClinPGx (the successor to PharmGKB) is a specialized resource for clinical pharmacogenomics, consolidating data from PharmGKB, CPIC, and PharmCAT. This skill enables Claude to programmatically query information regarding genetic variations affecting medication response, including gene-drug pairs, allele functions, and FDA drug labels. It is essential for developers and researchers building precision medicine applications, clinical decision support systems, or conducting pharmacogenetic research requiring evidence-based dosing recommendations.

Características Principales

Query gene-drug interactions and clinical practice guidelines from CPIC and DPWG
Access pharmacogenomic drug labeling from FDA and other regulatory agencies
8 GitHub stars
Retrieve detailed allele function, population frequency, and phenotype data
Fetch curated literature annotations with standardized evidence levels
Explore pharmacokinetic pathways showing drug metabolism and enzyme involvement

Casos de Uso

Building clinical decision support tools for genotype-guided medication dosing
Automating pharmacogenetic research and population-level genomic data analysis
Verifying drug safety risks based on patient genetic markers and HLA associations

Acerca de

Características Principales

Query gene-drug interactions and clinical practice guidelines from CPIC and DPWG
Access pharmacogenomic drug labeling from FDA and other regulatory agencies
8 GitHub stars
Retrieve detailed allele function, population frequency, and phenotype data
Fetch curated literature annotations with standardized evidence levels
Explore pharmacokinetic pathways showing drug metabolism and enzyme involvement

Casos de Uso

Building clinical decision support tools for genotype-guided medication dosing
Automating pharmacogenetic research and population-level genomic data analysis
Verifying drug safety risks based on patient genetic markers and HLA associations