Does this skill require an API key for access?

Basic access to the ClinPGx REST API via this skill does not currently require authentication, though significant users are encouraged to notify the ClinPGx team.

Is this tool suitable for automated clinical reporting?

While it provides the necessary data for reporting, it is designed as a tool for developers and researchers to build systems that should ultimately be reviewed by qualified healthcare professionals.

Which genetic variants are covered by the ClinPGx skill?

It covers all major pharmacogenes, including CYP450 enzymes (like CYP2D6 and CYP2C19), drug transporters (SLCO1B1), and HLA alleles associated with drug hypersensitivity.

Can Claude help interpret specific genotypes using this skill?

Yes, Claude can use this skill to look up allele functions and phenotypes to provide evidence-based interpretations based on CPIC guidelines.

What is the ClinPGx database?

ClinPGx is the clinical pharmacogenomics database that serves as the successor to PharmGKB, consolidating data from CPIC, PharmCAT, and regulatory bodies.

ClinPGx Pharmacogenomics Database

Name: ClinPGx Pharmacogenomics Database
Author: jimmc414

byjimmc414

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324

Ciencia de Datos y ML

Accesses comprehensive pharmacogenomic data for precision medicine, including gene-drug interactions and CPIC clinical guidelines.

Acerca de

The ClinPGx Database skill empowers Claude to retrieve and analyze critical pharmacogenomic information from the ClinPGx repository, the successor to PharmGKB. It provides developers and researchers with programmatic access to curated data on how genetic variations influence medication response, including CPIC evidence-based guidelines, allele frequencies, and regulatory drug labels. This tool is essential for building clinical decision support systems, conducting population health research, or implementing genotype-guided dosing protocols in digital health applications.

Características Principales

Retrieve curated gene-drug interaction data and clinical annotations
Query allele functions, phenotypes, and population frequencies
324 GitHub stars
Search FDA and international pharmacogenomic drug labeling
Explore pharmacokinetic and pharmacodynamic pathways
Access evidence-based CPIC clinical practice guidelines

Casos de Uso

Researching genetic risk factors for adverse drug reactions (ADR)
Building clinical decision support tools for personalized dosing
Automating gene panel analysis for precision medicine reports

Acerca de

Características Principales

Retrieve curated gene-drug interaction data and clinical annotations
Query allele functions, phenotypes, and population frequencies
324 GitHub stars
Search FDA and international pharmacogenomic drug labeling
Explore pharmacokinetic and pharmacodynamic pathways
Access evidence-based CPIC clinical practice guidelines

Casos de Uso

Researching genetic risk factors for adverse drug reactions (ADR)
Building clinical decision support tools for personalized dosing
Automating gene panel analysis for precision medicine reports