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This skill provides specialized guidance and implementation patterns for COBRApy, the standard Python library for constraint-based reconstruction and analysis (COBRA) of metabolic models. It empowers researchers and developers to conduct genome-scale metabolic simulations, perform Flux Balance Analysis (FBA) and Flux Variability Analysis (FVA), and execute gene knockout studies within an AI-assisted workflow. By integrating domain-specific best practices, this skill streamlines complex tasks like model management, flux sampling, and phenotype prediction for metabolic engineering and systems biology research.
