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The COSMIC Database skill provides a programmatic interface for Claude to interact with the Catalogue of Somatic Mutations in Cancer, the world's most comprehensive resource for human cancer mutations. It allows researchers and bioinformaticians to download curated datasets including the Cancer Gene Census, mutational signatures, structural variants, and drug resistance data. By automating the retrieval and initial processing of complex genomic files across different genome assemblies like GRCh37 and GRCh38, this skill streamlines cancer genomics pipelines and facilitates data-driven oncology research directly within the Claude Code environment.
