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This skill provides programmatic access to the Catalogue of Somatic Mutations in Cancer (COSMIC), the most comprehensive resource for exploring somatic mutations in human cancer. It enables researchers to automate the retrieval of millions of mutations across thousands of cancer types, access the expert-curated Cancer Gene Census, and download specific datasets like mutational signatures or drug resistance profiles. By streamlining the integration of COSMIC data into bioinformatics pipelines, it facilitates high-throughput cancer genomics analysis, clinical annotation, and target gene selection directly within your development environment.