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Histolab is a specialized toolkit designed to handle the complexities of gigapixel digital pathology images. It provides high-level abstractions for loading various Whole Slide Image (WSI) formats like SVS and NDPI, automatically segmenting tissue from background, and extracting informative tiles for downstream analysis. Whether you're performing exploratory sampling with random tiling, ensuring complete coverage with grid-based extraction, or prioritizing high-cellularity regions via score-based selection, Histolab streamlines the bridge between raw pathology slides and production-grade deep learning datasets.