What kind of data can I retrieve?

You can retrieve gene nomenclature, aliases, RefSeq sequences for transcripts and proteins, chromosomal maps, Gene Ontology (GO) annotations, and associated phenotypes.

Which NCBI APIs does this skill utilize?

This skill uses both NCBI E-utilities (ESearch, ESummary, EFetch) for complex queries and the newer NCBI Datasets API for streamlined metadata and sequence retrieval.

Which organisms are supported?

The skill supports all organisms indexed within the NCBI Gene database, including human, mouse, rat, and thousands of other eukaryotic and prokaryotic species.

Can I process multiple genes at once?

Yes, the skill includes a batch lookup script specifically designed to handle multiple gene symbols or IDs efficiently with built-in rate limiting.

Do I need an API key to use the Gene Database skill?

While not strictly required, using an NCBI API key is highly recommended as it increases your rate limit from 3-5 requests per second to 10 requests per second.

NCBI Gene Database

Name: NCBI Gene Database
Author: K-Dense-AI

byK-Dense-AI

•

3,719

Ciencia de Datos y ML

Queries and retrieves comprehensive genomic data from NCBI Gene using E-utilities and Datasets APIs for scientific analysis.

Acerca de

The NCBI Gene Database skill connects Claude directly to one of the world's most comprehensive genomic resources. It allows researchers and developers to search for genes by symbol or ID, retrieve reference sequences (RefSeqs), map chromosomal locations, and extract functional annotations such as Gene Ontology (GO) terms and phenotypes. By integrating both the legacy E-utilities and the modern NCBI Datasets API, this skill streamlines complex bioinformatics workflows, enabling automated batch lookups and deep data exploration within the Claude environment.

Características Principales

Detailed metadata retrieval including GO terms and RefSeqs
3,719 GitHub stars
Comprehensive search by gene symbol, ID, or biological context
Automatic rate limit management for NCBI API access
Efficient batch processing for large gene panels
Dual-API support for E-utilities and NCBI Datasets

Casos de Uso

Automating the annotation of gene lists for functional research
Validating gene identifiers and cross-referencing nomenclature across species
Retrieving chromosomal mapping and sequence data for bioinformatics pipelines

Acerca de

Características Principales

Detailed metadata retrieval including GO terms and RefSeqs
3,719 GitHub stars
Comprehensive search by gene symbol, ID, or biological context
Automatic rate limit management for NCBI API access
Efficient batch processing for large gene panels
Dual-API support for E-utilities and NCBI Datasets

Casos de Uso

Automating the annotation of gene lists for functional research
Validating gene identifiers and cross-referencing nomenclature across species
Retrieving chromosomal mapping and sequence data for bioinformatics pipelines