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The NCBI Gene Database skill provides a specialized interface for Claude to interact with the National Center for Biotechnology Information's genomic resources. It enables developers and bioinformaticians to search for genes by symbol or ID, retrieve detailed metadata—including reference sequences (RefSeqs), chromosomal maps, and Gene Ontology (GO) annotations—and perform complex biological context searches. By integrating both the traditional E-utilities and the modern Datasets API, this skill streamlines the process of functional analysis, sequence retrieval, and data validation, providing human-vetted scripts that handle rate limiting and multi-format outputs like JSON and FASTA.