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This skill empowers researchers and bioinformaticians to programmatically interface with the NCBI Gene Expression Omnibus (GEO), the world's largest public repository for functional genomics. It facilitates the discovery and retrieval of high-throughput data, including RNA-seq and microarray datasets. By automating the search for Series (GSE), Samples (GSM), and Platforms (GPL), and providing seamless integration with specialized libraries like GEOparse and Biopython, it streamlines the complex workflow of downloading metadata, expression matrices, and supplementary files for downstream computational analysis and meta-studies.
