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This skill equips Claude with the expertise to write, optimize, and simulate complex laboratory protocols using the Opentrons Protocol API v2. It provides comprehensive support for managing Flex and OT-2 robot hardware, including multi-channel pipettes and specialized modules like thermocyclers, heater-shakers, and magnetic blocks. Whether setting up serial dilutions, PCR preparations, or high-throughput plate replication, this skill ensures protocols follow best practices for liquid tracking, tip management, and hardware safety, enabling seamless transitions from code to wet-lab execution.