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This skill empowers researchers and developers to interact seamlessly with the Reactome pathway database, an open-source, curated resource for human biological processes. It facilitates complex bioinformatics tasks such as overrepresentation analysis of gene lists, mapping proteins to specific signaling pathways, and analyzing quantitative expression data to identify biological signatures. By providing direct integration with Reactome’s Content and Analysis REST APIs, it streamlines the workflow for systems biology studies, disease mechanism exploration, and comparative species analysis directly within the Claude Code environment.