Is a Reactome API key required to use this skill?

No, the Reactome REST API is open-source and free to use without an API key for standard queries and analysis tasks.

How long are analysis results available?

Analysis tokens generated by the Reactome service are valid for 7 days, allowing you to retrieve previously computed results without re-submission.

Does this skill support species other than humans?

While Reactome focuses on human pathways, the skill supports species projection to map identifiers from other organisms onto their human equivalents.

What types of identifiers are supported by the Reactome skill?

The skill supports various identifiers including UniProt accessions, Gene symbols (e.g., TP53), Ensembl IDs, EntrezGene IDs, and ChEBI IDs for small molecules.

Can I analyze quantitative expression data using this skill?

Yes, you can submit TSV-formatted expression data with numerical values to perform pathway analysis and find relevant biological processes.

Reactome Biological Pathway Analysis

Name: Reactome Biological Pathway Analysis
Author: Activer007

byActiver007

0•

Ciencia de Datos y ML

Queries the Reactome REST API to perform pathway enrichment analysis, gene mapping, and systems biology research directly within Claude.

This skill integrates the open-source Reactome pathway database into the Claude environment, enabling researchers and developers to conduct sophisticated systems biology studies. It allows for querying thousands of curated human pathways, performing overrepresentation and expression analysis on gene lists, and exploring molecular interactions through the Reactome Content and Analysis services. By providing programmatic access to high-quality biological data, this skill facilitates the identification of statistically significant pathways, disease mechanisms, and comparative species analysis, bridging the gap between raw genomic data and biological insight within your coding workflow.

Características Principales

010 GitHub stars

02Analyze gene expression datasets to identify relevant biological pathways

03Generate visualization links for the Reactome Pathway Browser

04Perform overrepresentation analysis on gene and protein lists

05Query detailed information on pathways, reactions, and molecular complexes

06Map identifiers across UniProt, Ensembl, Entrez, and ChEBI formats

Casos de Uso

01Identifying enriched biological pathways from a list of differentially expressed genes

02Exploring molecular mechanisms and participating entities in specific human disease pathways

03Mapping diverse biological identifiers to standardized Reactome pathway hierarchies

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add activer007/ordinary-claude-skills reactome-database

For use in Claude.ai and ChatGPT

Download Skill