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This skill implements the Fischbach & Walsh framework (Cell, 2024) to help researchers prioritize high-impact scientific problems over incremental execution. It provides a conversational interface for graduate students, postdocs, and PIs to pitch new ideas, troubleshoot stalled projects, and navigate complex research decision trees. By utilizing nine specialized sub-skills—including intuition pumps, risk assessment matrices, and optimization functions—it ensures that scientists spend more time choosing the right problem to work on before committing years to execution, ultimately maximizing the likelihood of significant discovery and career impact.