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The Vaex skill enables Claude to efficiently manipulate and visualize datasets with billions of rows by leveraging out-of-core DataFrames and lazy evaluation. It allows users to perform complex statistical analysis, create high-density visualizations, and build machine learning pipelines on datasets that would otherwise crash standard memory-reliant libraries. By utilizing memory-mapped file formats like HDF5 and Apache Arrow, this skill provides a powerful solution for scientific research, financial modeling, and large-scale data exploration without the need for expensive distributed clusters.