Enrichr

概要

Enrichr is a Model Context Protocol (MCP) server designed for comprehensive gene set enrichment analysis. It leverages the powerful Enrichr API to query a wide array of gene set libraries, including Gene Ontology, pathways, diseases, and drug-related datasets. The server efficiently filters results to return only statistically significant terms (p < 0.05), minimizing context usage while providing detailed insights into biological processes, molecular functions, and cellular components associated with a given gene list. It integrates seamlessly with MCP clients like Cursor, offering flexible configuration options for default libraries and output formats.

主な機能

• Multi-Library Gene Set Enrichment Analysis
• Specialized GO Biological Process enrichment with LLM-friendly descriptions
• Comprehensive support for hundreds of Enrichr gene set libraries
• Automated significance filtering (adjusted p < 0.05) to reduce noise
• Detailed output including p-values, scores, and overlapping genes
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ユースケース

• Interpreting gene expression data from high-throughput experiments (e.g., RNA-seq, microarray)
• Identifying significant biological processes and pathways associated with a gene list
• Uncovering functional implications of genes in various biological contexts