Are the dosing recommendations scientifically validated?

Yes, the skill provides access to Level 1A evidence from CPIC (Clinical Pharmacogenetics Implementation Consortium) and official FDA drug label annotations.

Does this skill require an API key?

No, basic access to the ClinPGx REST API is public and does not require authentication, though a rate limit of 2 requests per second is enforced.

What is the relationship between ClinPGx and PharmGKB?

ClinPGx is the clinical successor to PharmGKB, consolidating its data with CPIC and PharmCAT to provide updated, curated pharmacogenomic information.

What types of genes are covered in the database?

The database covers major pharmacogenes including CYP450 enzymes (like CYP2D6), transporters (SLCO1B1), and HLA genes involved in drug sensitivity.

ClinPGx Pharmacogenomics Database

Name: ClinPGx Pharmacogenomics Database
Author: Yezez9

byYezez9

0•

データサイエンスとML

Accesses comprehensive pharmacogenomics data, clinical guidelines, and gene-drug interactions for precision medicine applications.

The ClinPGx Database skill integrates the successor to PharmGKB directly into Claude's workflow, providing a robust resource for clinical pharmacogenomics. It allows for detailed queries regarding how genetic variations influence medication response by consolidating data from CPIC, PharmCAT, and major regulatory bodies. This skill is essential for researchers and developers building clinical decision support tools, as it provides programmatic access to evidence-based dosing guidelines, allele functions, and pharmacokinetic pathway mapping to help identify genetic risk factors for adverse drug reactions.

主な機能

01Analyze pharmacokinetic and pharmacodynamic pathway diagrams

02Access CPIC evidence-based dosing guidelines and strength ratings

03Explore FDA and regulatory pharmacogenomic drug labels

04Retrieve allele functions, frequencies, and phenotype data

05Query high-evidence gene-drug pairs and clinical annotations

060 GitHub stars

ユースケース

01Researching population-level allele frequencies for pharmacogenes

02Automating the identification of genetic risk factors in drug safety assessments

03Developing clinical decision support systems for genotype-guided dosing

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add yezez9/research-agent clinpgx-database

For use in Claude.ai and ChatGPT

主な機能

01Analyze pharmacokinetic and pharmacodynamic pathway diagrams

02Access CPIC evidence-based dosing guidelines and strength ratings

03Explore FDA and regulatory pharmacogenomic drug labels

04Retrieve allele functions, frequencies, and phenotype data

05Query high-evidence gene-drug pairs and clinical annotations

060 GitHub stars

ユースケース

01Researching population-level allele frequencies for pharmacogenes

02Automating the identification of genetic risk factors in drug safety assessments

03Developing clinical decision support systems for genotype-guided dosing

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add yezez9/research-agent clinpgx-database

For use in Claude.ai and ChatGPT