NCBI Gene Database Connector

概要

The NCBI Gene Database skill provides a specialized interface for Claude to interact with the National Center for Biotechnology Information's genomic resources. It enables developers and bioinformaticians to search for genes by symbol or ID, retrieve detailed metadata—including reference sequences (RefSeqs), chromosomal maps, and Gene Ontology (GO) annotations—and perform complex biological context searches. By integrating both the traditional E-utilities and the modern Datasets API, this skill streamlines the process of functional analysis, sequence retrieval, and data validation, providing human-vetted scripts that handle rate limiting and multi-format outputs like JSON and FASTA.

主な機能

• 8 GitHub stars
• Support for multiple data formats including JSON, XML, and FASTA
• Query NCBI Gene via E-utilities and Datasets APIs for comprehensive data
• Execute high-throughput batch gene lookups with automatic rate limiting
• Retrieve detailed metadata including RefSeqs, GO annotations, and phenotypes
• Search by biological context, pathways, or specific chromosomal locations

ユースケース

• Cross-referencing gene symbols with official nomenclature and IDs in research pipelines
• Building bioinformatics tools that require real-time functional and pathway data
• Automating gene annotation and metadata enrichment for genomic datasets