Can I search for genes by disease or phenotype?

Yes, the skill supports searching by biological context, including specific phenotypes, biological pathways, and Gene Ontology (GO) terms.

What data formats are supported?

You can retrieve gene data in several formats including JSON, XML, GenBank, FASTA, and human-readable text summaries.

Is it limited to human genes?

No, you can query genes across any organism supported by the NCBI database by specifying the taxon or organism name in your search parameters.

Does this skill require an NCBI API key?

While optional, an API key is recommended to increase rate limits from 3 to 10 requests per second for smoother data retrieval.

How does the skill handle multiple gene queries?

The skill includes a dedicated batch lookup script that efficiently processes lists of symbols or IDs while automatically managing NCBI's rate limits.

NCBI Gene Database Integration

Name: NCBI Gene Database Integration
Author: Yezez9

byYezez9

0•

データサイエンスとML

Queries the NCBI Gene database to retrieve comprehensive genetic information, sequences, and functional annotations.

This skill empowers Claude to interact directly with NCBI's vast genetic repositories using both E-utilities and the modern Datasets API. It streamlines the process of looking up gene symbols, retrieving Reference Sequences (RefSeqs), mapping chromosomal locations, and conducting functional analysis through Gene Ontology (GO) and pathway data. Ideal for bioinformaticians and researchers, it handles batch lookups and provides structured JSON or XML outputs for complex genomic workflows, ensuring accurate data retrieval with built-in rate limit handling.

主な機能

01Organism-specific filtering for accurate symbol mapping

02Batch retrieval of gene metadata and sequence information

03Detailed functional analysis via GO annotations and pathways

04Automated rate limit management and API key support

050 GitHub stars

06Dual API support for NCBI E-utilities and Datasets API

ユースケース

01Cross-referencing genes with specific phenotypes, diseases, or biological pathways

02Building automated bioinformatics pipelines for gene sequence retrieval

03Annotating lists of gene symbols with functional and positional data

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add yezez9/research-agent gene-database

For use in Claude.ai and ChatGPT

主な機能

01Organism-specific filtering for accurate symbol mapping

02Batch retrieval of gene metadata and sequence information

03Detailed functional analysis via GO annotations and pathways

04Automated rate limit management and API key support

050 GitHub stars

06Dual API support for NCBI E-utilities and Datasets API

ユースケース

01Cross-referencing genes with specific phenotypes, diseases, or biological pathways

02Building automated bioinformatics pipelines for gene sequence retrieval

03Annotating lists of gene symbols with functional and positional data

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add yezez9/research-agent gene-database

For use in Claude.ai and ChatGPT