Do I need an API key to use this skill?

No, the Open Targets GraphQL API used by this skill is public and does not require authentication for standard programmatic access.

What is the Open Targets Database skill?

It is a specialized capability for Claude that allows users to query the Open Targets Platform for biological, genetic, and pharmaceutical data to assist in drug discovery.

What kind of evidence does it provide for disease associations?

It retrieves evidence from multiple sources including human genetics, somatic mutations, known drugs, affected pathways, RNA expression, animal models, and scientific literature.

Can this skill help with drug repurposing?

Yes, by identifying drugs already associated with specific diseases and exploring their mechanisms of action, you can find opportunities for new therapeutic indications.

Open Targets Scientific Database

Name: Open Targets Scientific Database
Author: lifangda

bylifangda

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データサイエンスとML

Queries the Open Targets Platform to identify therapeutic drug targets, evaluate disease associations, and analyze clinical trial data.

概要

The Open Targets Database skill empowers Claude with programmatic access to one of the most comprehensive resources for therapeutic target identification and prioritization. By integrating human genetics, omics, and clinical evidence, it allows researchers to score target-disease associations and assess drug tractability or safety directly within their workflow. This tool is essential for evidence-based drug discovery, biological mechanism research, and competitive intelligence in pharmaceutical R&D.

主な機能

Search targets, diseases, and drugs via GraphQL API
Analyze target-disease association scores and evidence
Evaluate gene tractability and safety liabilities
Access clinical trial phases and drug mechanisms of action
Retrieve multi-source evidence including genetics and literature
16 GitHub stars

ユースケース

Identifying and prioritizing potential therapeutic targets for specific diseases
Validating target druggability and safety profiles during early-stage R&D
Conducting drug repurposing research by analyzing known drug mechanisms