UniProt Database Integration

概要

This skill provides a specialized interface for Claude to interact with the UniProt protein sequence and functional information resource, allowing developers and researchers to automate complex bioinformatics workflows. It simplifies tasks such as searching for protein entries by gene symbol or accession, retrieving sequences for analysis, mapping identifiers between major databases like Ensembl and PDB, and accessing detailed functional annotations from both curated Swiss-Prot and computer-annotated TrEMBL datasets. By providing standardized access to the UniProt REST API, it bridges the gap between AI coding assistants and the world's leading protein knowledgebase.

主な機能

• Automated ID mapping between UniProt and over 40 external databases
• Support for streaming large datasets and customizing specific data fields
• Access to detailed functional annotations, GO terms, and protein domains
• Bulk retrieval of protein sequences in FASTA, JSON, and TSV formats
• 1 GitHub stars
• Advanced protein search using natural language or structured boolean syntax

ユースケース

• Automating the retrieval of protein sequences for structural biology and folding pipelines
• Programmatically querying protein functional annotations to enrich experimental datasets
• Mapping large lists of gene identifiers to UniProt accessions for multi-omic data integration