What is the difference between Swiss-Prot and TrEMBL in this skill?

Swiss-Prot entries are manually curated and reviewed for high quality, while TrEMBL entries are computationally analyzed. You can filter for reviewed entries using the 'reviewed:true' query parameter.

Can this skill search for specific human genes?

Yes, you can use structured queries like 'gene:BRCA1 AND organism_id:9606' to find specific human proteins and their associated data.

Does it support mapping identifiers from other databases?

Yes, it includes robust ID mapping capabilities for dozens of databases including Ensembl, RefSeq, PDB, and AlphaFoldDB.

Can I download protein sequences in bulk?

Yes, the skill supports both batch retrieval of specific accessions and a streaming endpoint for downloading large datasets that exceed standard pagination limits.

UniProt Database Search & Mapping

Name: UniProt Database Search & Mapping
Author: lifangda

bylifangda

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データサイエンスとML

Accesses the UniProt knowledgebase to search, retrieve, and map protein sequence and functional information.

This skill provides a specialized interface for the UniProt REST API, allowing Claude to perform complex protein database operations directly. It supports searching by gene, organism, or accession, retrieving sequences in FASTA format, and performing large-scale ID mapping across databases like Ensembl, RefSeq, and PDB. It is essential for bioinformatics workflows, protein analysis, and scientific data collection where precise, manually curated (Swiss-Prot) or computationally predicted (TrEMBL) protein data is required.

主な機能

0116 GitHub stars

02Batch retrieval and streaming for large-scale protein datasets

03Granular field selection to optimize data transfer and processing

04Cross-database ID mapping for Ensembl, RefSeq, PDB, and more

05FASTA sequence retrieval and protein functional annotation access

06Advanced search syntax for gene names, organisms, and protein accessions

ユースケース

01Filtering and searching for reviewed Swiss-Prot entries with specific functional domains

02Automating protein sequence retrieval for bioinformatics pipelines

03Mapping large lists of identifiers between UniProt and other scientific databases

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add lifangda/claude-plugins uniprot-database

For use in Claude.ai and ChatGPT

Download Skill