Lancet Study Design & Registration
Validates clinical study designs, prospective trial registrations, and statistical analysis plans to meet strict Lancet and ICMJE submission standards.
Lancet Study Design & Registration helps medical researchers and clinical trial authors audit study designs and satisfy rigorous Lancet and ICMJE publication standards. It checks prospective trial registration dates against first participant enrollment, identifies discrepancies between pre-specified protocols and reported endpoints, evaluates randomization and allocation concealment rigor, and verifies intention-to-treat (ITT) statistical analysis plans to prevent desk rejection.
주요 기능
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02Audit pre-specified statistical analysis plans (SAP) to identify endpoint switching or missing data strategies
03Check statistical power calculations, sample size justifications, and intention-to-treat (ITT) populations
04Verify prospective clinical trial registration timing across ClinicalTrials.gov, ISRCTN, and WHO-ICTRP
05Evaluate RCT design rigor including sequence generation, allocation concealment, and blinding protocols
06Validate observational study methodologies, confounding adjustment approaches, and calibrated causal claims
사용 사례
01Structuring author responses to peer reviewer critiques regarding trial design, power, or outcome deviations
02Auditing study protocols, registration dates, and SAP consistency prior to draft submission
03Preparing randomized controlled trial (RCT) manuscripts for submission to The Lancet and its specialty journals