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Ensembl

Provides seamless access to the Ensembl REST API for genomic data, comparative genomics, and biological annotations.

About

This server enables seamless access to Ensembl's vast genomic database through a standardized Model Context Protocol (MCP) interface. It empowers users to retrieve detailed gene and transcript information, extract diverse sequence data, perform comparative genomics, analyze genetic variants, and access regulatory features across multiple species. By standardizing access to Ensembl's extensive resources, it makes complex genomic queries accessible, especially for natural language processing tools like Claude Desktop.

Key Features

  • Analyze genetic variants, predict their consequences, and retrieve population data
  • Retrieve diverse sequence data, including genomic DNA and CDS sequences
  • Efficiently process batch requests for multiple genes or genomic regions
  • Perform comparative genomics for homolog detection and gene family trees
  • Access comprehensive gene and transcript information by ID or symbol
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Use Cases

  • Analyzing genetic variants within a genomic region and predicting their effects
  • Retrieving detailed information and sequences for specific genes like BRCA2
  • Finding orthologous or paralogous genes across different species for comparative analysis