VCF Agent
byjda
0Facilitates genomic variant analysis by exposing Variant Calling Format (VCF) files to Large Language Model (LLM) agents.
About
Leveraging LLM agents for genomic variant analysis is streamlined with this server, which provides an interface to Variant Calling Format (VCF) files. Designed for use with a single VCF file in a desktop or confidential compute VM setting, it enables powerful queries by genomic position, region, or variant ID. This allows LLMs to interact with and extract insights from complex genetic data efficiently, supporting both compressed and uncompressed VCF formats with indexing capabilities.
Key Features
- Optimized for bgzip-compressed VCF files with tabix indexes for efficient querying.
- Supports both standard I/O and HTTP/SSE transports for flexible integration.
- Search for variants using their unique IDs (e.g., rsIDs).
- Retrieve variants within a defined genomic region (start and end positions).
- Query genomic variants by specific chromosome and position.
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Use Cases
- Exploring and interacting with single VCF files in isolated or confidential computing environments.
- Automating complex genomic variant analysis workflows using LLM agents.
- Integrating VCF data query capabilities into LLM-driven bioinformatics tools and services.
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