COSMIC Cancer Gene Toolkit

The COSMIC Toolkit enables bioinformaticians and researchers to programmatically validate gene lists against the expert-curated Catalogue Of Somatic Mutations In Cancer (COSMIC). By integrating directly with the Cancer Gene Census, this skill allows users to retrieve critical metadata including gene tiers, somatic and germline roles, and specific tumor types. It is designed to streamline oncology workflows, such as filtering variant calling results (VCFs) or performing functional gene enrichment, by providing structured JSON output that integrates easily with downstream command-line tools.

Key Features

Use Cases