Genomic Feature Annotation & Visualization

About

Simplifies the complex task of genomic feature mapping by automating the use of Homer’s annotatePeaks.pl tool to identify target genes and genomic context. This skill guides users through preparing BED files, managing genome assemblies, and performing detailed annotations for transcription factor peaks, histone modifications, or ATAC-seq data. Beyond raw data, it generates insightful statistical summaries and visual representations—including pie charts and bar plots—enabling researchers to quickly interpret the biological significance of their genomic intervals.

Key Features

• Automatic validation and installation of genome assemblies
• Automated annotation of promoters, exons, introns, and intergenic regions
• Visual reporting of results via customizable pie charts and bar plots
• Seamless integration with Homer's annotatePeaks.pl for high-accuracy mapping
• 2 GitHub stars
• Generation of comprehensive statistical summaries and feature distribution logs

Use Cases

• Standardizing and annotating BED, narrowPeak, or broadPeak files for downstream analysis
• Characterizing the genomic distribution of histone modifications or chromatin accessibility peaks
• Identifying potential target genes for transcription factors by analyzing promoter proximity