What is the 'Life Threshold' defined in this skill?

It follows the principle that molecules with an Assembly Index (MA) greater than 15 and a copy number greater than 1 are too complex to arise by random chance, signaling a biological origin.

What is the significance of the Trit -1 value?

In its ecosystem, a Trit of -1 signifies that this skill acts as a validator or constraint, focusing on complexity measurement and validation rather than synthesis execution.

Can I integrate this with mass spectrometry results?

Yes, the skill includes specialized logic to reconstruct assembly DAGs from tandem mass spectrometry (MS2) peaks to estimate complexity.

How does the skill compute the assembly index?

It uses dynamic programming over a molecular Directed Acyclic Graph (DAG) to find the shortest possible construction sequence from basic primitives.

Molecular Assembly Index

Name: Molecular Assembly Index
Author: plurigrid

byplurigrid

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Data Science & ML

Computes molecular complexity using Lee Cronin's Assembly Theory to identify biosignatures and calculate minimal construction pathways.

The Assembly Index skill enables Claude to perform advanced chemical complexity analysis based on Assembly Theory principles. By calculating the minimum number of joining operations required to construct a molecule from basic building blocks, it provides a quantitative metric for complexity. This skill is specifically designed for researchers and scientists who need to validate biosignatures (where MA > 15), analyze molecular directed acyclic graphs (DAGs), and integrate mass spectrometry data into complexity assessments, effectively bridging the gap between raw chemical data and biological significance.

Key Features

01Calculates minimal assembly steps for complex molecular construction

02Integrates with tandem mass spectrometry (MS2) data for complexity estimation

03Provides dynamic programming pathways for shortest construction sequences

047 GitHub stars

05Identifies life signatures using the MA > 15 and copy number thresholds

06Generates and analyzes molecular Directed Acyclic Graphs (DAGs)

Use Cases

01Quantifying the structural complexity of synthetic chemical compounds in a laboratory setting

02Analyzing mass spectrometry fragmentation patterns to estimate molecular assembly indices

03Validating whether discovered molecules are potential biosignatures in astrobiology

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add plurigrid/asi assembly-index

For use in Claude.ai and ChatGPT

Download Skill