UniProt Protein Database FAQs

Question 1

What protein data can I access with this skill?

Accepted Answer

You can access protein sequences, gene names, functional annotations, GO terms, and cross-references from both the Swiss-Prot (manually curated) and TrEMBL (automatically annotated) databases.

Question 2

How do I ensure I am only getting high-quality, reviewed data?

Accepted Answer

You can use the 'reviewed:true' filter in your search queries to specifically target Swiss-Prot entries, which have been manually reviewed by UniProt curators.

Question 3

Does this skill support large-scale data exports?

Accepted Answer

Yes, it utilizes the UniProt stream endpoint to handle large result sets that exceed standard pagination limits, making it suitable for downloading complete datasets.

Question 4

Is there a limit to how many IDs I can process at once?

Accepted Answer

The integrated UniProt mapping workflow supports jobs of up to 100,000 identifiers per request, with results stored on the server for 7 days.

Question 5

Can I map IDs from other databases like Ensembl or PDB?

Accepted Answer

Yes, the skill supports the UniProt ID mapping service, allowing you to convert identifiers between UniProt and dozens of external databases including Ensembl, RefSeq, PDB, and AlphaFoldDB.

UniProt Protein Database

Key Features

Use Cases

UniProt Protein Database

Key Features

Use Cases