MySQL enables Large Language Models (LLMs) to securely interact with MySQL databases. It offers functionalities for executing read-only SELECT queries, listing database tables, showing table structures, and viewing schema information. Furthermore, it supports write operations such as INSERT, UPDATE, and DELETE with transaction support, parameterized queries for data safety, and returns affected rows and insert IDs. Security features include read-only transaction mode for SELECT queries, query length and result size limits, performance monitoring and logging, and automatic transaction handling.