PubMed Smithery is a Model Content Protocol (MCP) server designed to enhance the process of searching and retrieving academic papers from the PubMed database. It extends beyond basic keyword searches, offering functionalities like MeSH (Medical Subject Headings) term lookup to refine search terms, publication count statistics for comparing the prevalence of different concepts, and structured PICO (Population, Intervention, Comparison, Outcome) based evidence search to aid in evidence-based literature reviews. By providing these features, PubMed Smithery streamlines research workflows and improves the efficiency of finding relevant scientific literature.