Does it support biomarker-guided therapy?

Yes, it excels at biomarker integration, including genomic alterations (mutations, CNV), gene expression signatures, IHC markers, and PD-L1 scoring to stratify patient cohorts.

What statistical analyses can this skill perform?

The skill supports comprehensive statistical reporting including Hazard Ratios, p-values, 95% Confidence Intervals, survival analysis (OS, PFS), and Cox regression modeling.

How does it handle evidence quality?

It utilizes the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) system to categorize the strength of recommendations and the quality of evidence.

Is this skill intended for direct patient care at the bedside?

No, this skill is specifically designed for pharmaceutical research, drug development, and population-level guideline creation. For individual patient treatment plans, the 'treatment-plans' skill is recommended.

What is the output format for the documents?

The skill generates publication-ready LaTeX code, which produces professional PDF documents optimized for regulatory submissions and scientific journals.

Clinical Decision Support Writer

Name: Clinical Decision Support Writer
Author: jimmc414

byjimmc414

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324

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数据科学与机器学习

Generates professional, publication-ready clinical decision support documents and biomarker-stratified cohort analyses in LaTeX format.

This skill empowers researchers and pharmaceutical professionals to automate the creation of high-quality clinical decision support (CDS) documents, including patient cohort analyses and evidence-based treatment guidelines. It specializes in integrating complex biomarker data with statistical outcomes—such as hazard ratios and survival curves—and applies the GRADE system for rigorous evidence grading. By outputting publication-ready LaTeX/PDF files, it streamlines the development of regulatory submissions, clinical trial reports, and medical strategy documents, ensuring consistent formatting and professional presentation of molecular and clinical data.

主要功能

01Visual executive summaries with color-coded key findings and boxes

02Evidence-based treatment recommendations with GRADE grading (1A-2C)

03Biomarker-stratified patient cohort analysis and subgroup comparisons

04324 GitHub stars

05Advanced statistical reporting including Hazard Ratios, OS, and PFS

06Publication-ready LaTeX output with TikZ-based decision algorithms

使用场景

01Generating biomarker-guided drug efficacy reports for Phase 2/3 clinical trial analysis

02Developing formal clinical practice guidelines and evidence-synthesis for medical societies

03Creating companion diagnostic documentation linking molecular subtypes to treatment response

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add jimmc414/kosmos clinical-decision-support

For use in Claude.ai and ChatGPT

Download Skill