ClinPGx Pharmacogenomics Database

关于

The ClinPGx Database skill empowers Claude to retrieve and analyze critical pharmacogenomic information from the ClinPGx repository, the successor to PharmGKB. It provides developers and researchers with programmatic access to curated data on how genetic variations influence medication response, including CPIC evidence-based guidelines, allele frequencies, and regulatory drug labels. This tool is essential for building clinical decision support systems, conducting population health research, or implementing genotype-guided dosing protocols in digital health applications.

主要功能

• Retrieve curated gene-drug interaction data and clinical annotations
• Query allele functions, phenotypes, and population frequencies
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• Search FDA and international pharmacogenomic drug labeling
• Explore pharmacokinetic and pharmacodynamic pathways
• Access evidence-based CPIC clinical practice guidelines

使用场景

• Researching genetic risk factors for adverse drug reactions (ADR)
• Building clinical decision support tools for personalized dosing
• Automating gene panel analysis for precision medicine reports