Hi-C Loop Calling

Streamlines the identification of chromatin loops by providing a structured workflow that handles data conversion, chromosome naming normalization, and loop detection using the cooltools suite. It automates essential preprocessing steps such as generating chromosome-arm view files and calculating expected cis-contacts, ultimately producing visualization-ready BEDPE files for tools like IGV. This skill is ideal for researchers working with Hi-C datasets who need a reproducible and efficient way to map long-range genomic interactions while ensuring data consistency across different genome assemblies.

主要功能

使用场景