How does this skill help with drug discovery?

It allows users to identify drug-target interactions, find protein-protein interactions, and discover potential drug repurposing opportunities by analyzing network paths.

What biological entities can I search for?

You can search for a wide range of entities including genes, proteins, drugs, diseases, and clinical phenotypes (signs and symptoms).

Does this skill require external API access?

No, this skill is designed to query a local version of the PrimeKG dataset stored in CSV format, ensuring high-speed access to the knowledge graph.

PrimeKG (Precision Medicine Knowledge Graph) is a comprehensive data resource that integrates over 20 primary databases to provide a holistic view of diseases, drugs, and phenotypes.

PrimeKG Precision Medicine Explorer

Name: PrimeKG Precision Medicine Explorer
Author: youyinnn

byyouyinnn

0•

数据科学与机器学习

Queries the Precision Medicine Knowledge Graph to analyze associations between genes, drugs, diseases, and phenotypes.

The PrimeKG Precision Medicine Explorer is a specialized skill that allows Claude to programmatically interact with the Harvard MIMS Precision Medicine Knowledge Graph (PrimeKG). By integrating data from over 20 primary databases and high-quality literature, it provides access to over 100,000 nodes and 4 million edges. This skill is essential for researchers and developers working in bioinformatics, enabling them to navigate complex biological networks, identify drug-target interactions, and bridge the gap between molecular genetics and clinical outcomes within their coding environment.

主要功能

01Identification of drug-disease paths for repurposing opportunities

020 GitHub stars

03Semantic search for genes, proteins, drugs, and diseases

04Comprehensive disease context and phenotype summarization

05Direct neighbor retrieval for clinical evidence and associations

06Support for 29 relationship types including PPIs and GWAS evidence

使用场景

01Correlating clinical phenotypes with genetic markers for diagnostic research

02Identifying novel molecular targets for specific disease mechanisms

03Screening existing drugs for potential new indications via network pharmacology

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add youyinnn/skills-collection primekg

For use in Claude.ai and ChatGPT