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PubMed Research Assistant empowers Claude to perform deep literature searches and data extraction from the U.S. National Library of Medicine. It enables complex Boolean queries using MeSH terms, systematic review automation through the PICO framework, and programmatic access via the E-utilities REST API. Whether you are conducting meta-analyses, building automated literature monitoring workflows, or retrieving specific citations, this skill provides the precision tools needed to navigate and process millions of life science records.