Reactome Database Integration

关于

This skill empowers researchers and bioinformaticians to perform complex systems biology tasks directly through Claude, including pathway enrichment analysis, gene-to-pathway mapping, and the exploration of molecular interactions. By leveraging the Reactome REST API and Python client, it facilitates the analysis of gene expression datasets, identification of statistically significant biological pathways, and visualization of results. It is an essential tool for high-throughput biological data interpretation, providing access to over 2,800 human pathways and tens of thousands of curated reactions.

主要功能

• Direct access to Reactome Content and Analysis REST APIs
• Quantitative expression data analysis for pathway identification
• Support for multiple identifier types including UniProt, Ensembl, and Entrez
• Automated species projection to map non-human data to human pathways
• Overrepresentation analysis for gene and protein lists
• 16 GitHub stars

使用场景

• Identifying enriched pathways from experimental gene or protein lists
• Automating bioinformatics workflows using the reactome2py Python package
• Exploring disease-related molecular mechanisms and interactions