Can I analyze my own gene expression data?

Yes, the skill supports expression data analysis using TSV formats where you provide identifiers and numeric expression values for multiple samples.

How long do the analysis results remain available?

Analysis tokens generated by the Reactome Analysis Service are valid for 7 days, allowing you to retrieve or share results across different sessions.

Which biological identifiers does the Reactome skill support?

It supports a wide range of identifiers including UniProt accessions, Gene symbols, Ensembl IDs, EntrezGene IDs, and ChEBI IDs for small molecules.

Is the reactome2py Python package required?

No, while the skill provides guidance for reactome2py, it also includes direct REST API implementations which are often preferred for the most up-to-date functionality.

Can I visualize the analysis results?

Yes, the skill can generate specific URLs that link your computed analysis tokens directly to the Reactome Pathway Browser for interactive web-based visualization.

Reactome Pathway Analysis

Name: Reactome Pathway Analysis
Author: plurigrid

byplurigrid

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数据科学与机器学习

Integrates the Reactome pathway database to perform biological enrichment analysis, gene mapping, and molecular interaction queries for systems biology research.

This skill empowers researchers and bioinformaticians to interact with the Reactome knowledgebase directly through Claude. It provides specialized capabilities for performing overrepresentation and expression analysis, mapping gene/protein lists to human pathways, and exploring complex molecular interactions across over 2,800 human pathways. Whether you are investigating disease mechanisms, analyzing differential expression data, or visualizing results in the Reactome Pathway Browser, this skill streamlines the transition from raw biological data to actionable pathway insights using both REST APIs and Python-based workflows.

主要功能

01Overrepresentation analysis for gene and protein identifier lists

02Automated mapping of UniProt, Ensembl, and Entrez IDs to pathways

03Visualization support for analysis results in the Reactome Pathway Browser

04Quantitative expression data analysis with TSV support

058 GitHub stars

06Direct retrieval of molecular interactions and pathway hierarchies via REST API

使用场景

01Identifying statistically significant pathways from differential expression datasets

02Retrieving participating proteins and small molecules for specific metabolic pathways

03Mapping clinical gene variants to specific biological processes and disease mechanisms

What are Skills?·How to Install

Install with 🐟 Skill.Fish

npx skillfish add plurigrid/asi reactome-database

For use in Claude.ai and ChatGPT

Download Skill