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The Scientific Critical Thinking skill empowers Claude to perform high-level analytical reviews of research papers and experimental designs. By applying systematic frameworks like GRADE and Cochrane Risk of Bias, it identifies confounding variables, detects researcher bias, and assesses the strength of evidence in systematic reviews. This skill is essential for researchers and data scientists who need to validate the integrity of scientific claims, interpret complex statistical results, and ensure that experimental methodologies align with industry-standard best practices.