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This skill empowers Claude to perform systematic reviews and critical analyses of scientific literature by applying rigorous evaluation frameworks. It assesses experimental designs for internal and external validity, identifies subtle researcher and selection biases, evaluates the soundness of statistical interpretations, and detects logical fallacies in scientific arguments. Whether reviewing academic papers or conducting meta-analyses, this skill provides a structured approach to determining the strength of evidence using industry standards like GRADE and Cochrane Risk of Bias.